Fucidin Tablet

Indications

Acne vulgaris, Skin infections, Conjunctivitis, staphylococcal infections

Adult Dose

Oral Susceptible infections Adult: 500 mg tid. May increase to 1 g tid in fulminating infections.

Child Dose

Oral Susceptible infections Child: <1 yr: About 15 mg/kg; 1-5 yr: 250 mg; 5-12 yr: 500 mg. Doses to be taken tid.

Administration

Should be taken with food.

Contra Indications

Hypersensitivity.

Precautions

Hepatic disease; monitor liver function. Neonates; pregnancy, lactation.

Pregnancy-Lactation

Not Classi

Interactions

Synergistic action with antistaphylococcal penicillin. Antagonism with ciprofloxacin.

Adverse Effects

Jaundice and liver dysfunction (reversible); GI disturbances. IV: Venospasm, thrombophloebitis and haemolysis; hypocalcaemia. SC/IM: Tissue necrosis. Topical: Rashes and irritation.

Mechanism of Action

Fusidic acid disrupts translocation of peptide subunits and elongating the peptide chain of susceptible bacteria, thus inhibiting protein synthesis.

Note

Fucidin Tablet manufactured by Leo Pharmaceutical Products,Denmark. Its generic name is Sodium Fusidate (Fusidic Acid).