Natri-SR Tablet

Indapamide
1.5mg
Renata PLC.
Pack size30's pack
Retail Price5

Indications

Hypertension, Congestive heart failure

Adult Dose

Oral Hypertension Adult: 1.25-2.5 mg once daily, alone or in conjunction with other antihypertensives. Oedema Adult: 2.5 mg once daily increased to 5 mg daily after 1 wk if needed.

Child Dose

Safety & efficacy not established

Administration

Should be taken with food.

Contra Indications

Anuria, severe hepatic impairment.

Precautions

Pregnancy, lactation, elderly, renal impairment, fluid or electrolyte imbalance, hyperuricaemia, DM, lupus erythematosus. Lactation: not known if excreted into breast milk, avoid

Pregnancy-Lactation

B Pregnancy Category: B Lactation: not known if excreted into breast milk, avoid

Interactions

Additive effect with other antihypertensive agents and diuretics. Increased chance of hypokalaemia with corticosteroids, corticotropin and amphotericin. Potentially Fatal: Increased risk of lithium toxicity. Hypokalaemia enhances digitalis toxicity with cardiac gycosides.

Adverse Effects

1-10% Hypotension,Palpation,Flushing,Dizziness,Lightheadedness,Vertigo,Headache,Weakness,Restlessness,Drowsiness,Fatigue,Lethargy,Malaise,Anorexia,Nausea/vomiting,Nocturia,Polyuria,Blurred vision,Rhinnorhea,Electrolyte abnormalities,Pruritus,Rash <1% Cutaneous vasculitis,Glycosuria,Pancreatitis

Mechanism of Action

Indapamide enhances excretion of sodium, chloride and water by interfering with the transport of sodium ions across the renal tubular epithelium.

Note

Natri-SR 1.5mg Tablet manufactured by Renata PLC.. Its generic name is Indapamide.

Some other brands of Indapamide