Natrilix Tablet

Indapamide
2.5 mg
Les Laboratories Servier Industrie,France
Pack size10's pack
Retail Price

Indications

Hypertension, Congestive heart failure

Adult Dose

Oral Hypertension Adult: 1.25-2.5 mg once daily, alone or in conjunction with other antihypertensives. Oedema Adult: 2.5 mg once daily increased to 5 mg daily after 1 wk if needed.

Child Dose

Safety & efficacy not established

Administration

Should be taken with food.

Contra Indications

Anuria, severe hepatic impairment.

Precautions

Pregnancy, lactation, elderly, renal impairment, fluid or electrolyte imbalance, hyperuricaemia, DM, lupus erythematosus. Lactation: not known if excreted into breast milk, avoid

Pregnancy-Lactation

B Pregnancy Category: B Lactation: not known if excreted into breast milk, avoid

Interactions

Additive effect with other antihypertensive agents and diuretics. Increased chance of hypokalaemia with corticosteroids, corticotropin and amphotericin. Potentially Fatal: Increased risk of lithium toxicity. Hypokalaemia enhances digitalis toxicity with cardiac gycosides.

Adverse Effects

1-10% Hypotension,Palpation,Flushing,Dizziness,Lightheadedness,Vertigo,Headache,Weakness,Restlessness,Drowsiness,Fatigue,Lethargy,Malaise,Anorexia,Nausea/vomiting,Nocturia,Polyuria,Blurred vision,Rhinnorhea,Electrolyte abnormalities,Pruritus,Rash <1% Cutaneous vasculitis,Glycosuria,Pancreatitis

Mechanism of Action

Indapamide enhances excretion of sodium, chloride and water by interfering with the transport of sodium ions across the renal tubular epithelium.

Note

Natrilix 2.5 mg Tablet manufactured by Les Laboratories Servier Industrie,France. Its generic name is Indapamide.

Some other brands of Indapamide