Undenatured Type II Collagen + Boswellia Serrata

Osteoarthritis and its associated pain and inflammation

1 capsule daily or as advised by the registered physician.

Contraindicated in patient with known hypersensivity to chicken or egg.

Scientific information is limited on the use of Undenatured collagen type II & Boswellia Serrata Extract during pregnancy or lactation.

Well tolerated in the recommended dose. Constipation and headache may have occurred at high dose.

Undenatured Type II Collagen molecules contain active binding sites called epitopes which trigger the process of oral tolerization. Through oral tolerization process, active epitopes of Undenatured Type II Collagen interact with Peyer's patches (lymphoid tissue) of small intestine to release collagen-specifc regulatory T-cells. Collagen-specifc regulatory T-cells then migrate to joint areas and prevent release of T-cells which are destructive for joint cartilage. It prevents the secretion of collagenase enzymes by macrophages responsible for breakdown of collagen in joint cartilage. It also slows the production of inflammatory cytokines resulting in reduction of inflammation, halting the erosion of joint cartilage and promote cartilage rebuilding. Boswellia serrata extract suppresses leukotriene formation by inhibiting the 5-lipooxygenase enzyme and reduces production of inflammatory mediators. Thus it reduces pain and inflammation.