Sodium sulfacetamide + Sulfur topical
Indications
Acne, Seborrheic Dermatitis
Adult Dose
Acne
Indicated in the topical control of acne vulgaris and rosacea
Cream: Cleanse thoroughly with soap and water before applying thin layer to affected areas qDay/TID PRN
Foam: Cleanse thoroughly before massaging foam into affected area qDay-BID; if removing, rinse off after 1-2 minutes
Cleanser: Apply to wet skin and massage gently qDay/BID; rinse thoroughly and pat dry
Cleansing Pads: Apply wet pad to wet skin and work into full lather for 10-20 seconds, avoiding eyes; rinse thoroughly and pat dry; discard used
To minimize potential dryness, start with 1 application daily, then gradually increase to 2-3 times daily as needed
Seborrheic Dermatitis
Indicated in the topical control of acne vulgaris and rosacea
Cream: Cleanse thoroughly with soap and water before applying thin layer to affected areas qDay/TID PRN
Foam: Cleanse thoroughly before massaging foam into affected area qDay-BID; if removing, rinse off after 1-2 minutes
Cleanser: Apply to wet skin and massage gently qDay/BID; rinse thoroughly and pat dry
Cleansing Pads: Apply wet pad to wet skin and work into full lather for 10-20 seconds, avoiding eyes; rinse thoroughly and pat dry; discard used
To minimize potential dryness, start with 1 application daily, then gradually increase to 2-3 times daily as needed
Child Dose
Acne Vulgaris
Adolescents
Cream: Cleanse thoroughly with soap and water before applying thin layer to affected areas qDay/TID PRN
Foam: Cleanse thoroughly before massaging foam into affected area qDay-BID; if removing, rinse off after 1-2 minutes
Cleanser: Apply to wet skin and massage gently qDay/BID; rinse thoroughly and pat dry
Cleansing Pads: Apply wet pad to wet skin and work into full lather for 10-20 seconds, avoiding eyes; rinse thoroughly and pat dry; discard used
To minimize potential dryness, start with 1 application daily, then gradually increase to 2-3 times daily as needed
Contra Indications
Hypersensitivity to sulfa drugs
Precautions
External use only
Avoid contact with eyes or mucous membranes
Avoid UV exposure
Discontinue if excessive skin irritation develops
Severe reactions including Stevens-Johnson syndrome, toxic epidermal necrolysis, fulminant hepatic necrosis, agranulocytosis, aplastic anemia, and other blood dyscrasias reported
Pregnancy-Lactation
C
Pregnancy Category: C
Lactation: Unknown whether excreted in breast milk, use caution
Adverse Effects
Frequency Not Defined
Local irritation
Pruritus
Erythema
Itching
Edema
Mechanism of Action
Sulfacetamide: Para-aminobenzoic acid (PABA) inhibitor; restricts folic acid synthesis required for bacterial growth
Sulfur: Elicits antiseptic, antiparasitic, antiseborrheic, and keratolytic actions