Methi + Gurmar
Indications
Diabetes, High blood pressure, Antioxidant, Neuroprotective
Adult Dose
1-2 Capsules should be taken 30 minutes before meal twice daily or as prescribed by the physician.
Contra Indications
There is no known contraindication.
Pregnancy-Lactation
Not recommended for pregnant and lactating mother. If necessary before taking pregnant or breast-feeding women should talk to the physician.
Adverse Effects
No significant side effect has been observed in proper dosage.
Mechanism of Action
The mechanism of action by which fenugreek seeds act as an antidiabetic agent may be achieved via activating of insulin synthesis and its releasing from the pancreatic ?-cells . Moreover, a clinical study showed that the antidiabetic effect of fenugreek was through increasing of insulin sensitivity. As an antihyperglycemic agent, the mode of action entails decreasing hepatic glucose production and the intestinal absorption of glucose and increasing peripheral glucose uptake and utilization.
The mode of action of the drug is through stimulation in insulin secretion from pancreas. It also exerts a similar effect by delaying the glucose absorption in the blood. The atomic arrangements of gymnemic acids to the taste buds are similar to sugar molecules which fill the receptors in the taste buds preventing its activation by the sugar molecule in the food. Similarly, in the intestine it attaches to the receptor present in external layer of intestine, thereby preventing the absorption of sugar molecules by intestine, leading to reduction in blood sugar levels