Iodoquinol
Indications
Intestinal Amebiasis
Adult Dose
Intestinal Amebiasis
650 mg PO PC q8hr for 20 days; not to exceed 2 g/day
Child Dose
Intestinal Amebiasis
30-40 mg/kg/day divided PO PC q8hr PO for 20 days; not to exceed 1.95 g/day
Contra Indications
Hypersensitivity to 8-hydroxyquinolones or iodoquinol
Iodine sensitivity
Pre-existing optic neuropathy
Hepatic damage
Precautions
Caution in thyroid disease
Interferes with thyroid tests for up to 6 months after discontiunation
Do not repeat course before 2-3 wk
Not effective in amebic hepatitis or liver abscess
Avoid long term thearpy (associated with optic neuritis and optic atrophy)
Pregnancy-Lactation
C
Pregnancy Category: C
Lactation: unknown
Adverse Effects
Frequency Not Defined
Headache
Chills
Agitation
Diarrhea
Rash
Fever
Urticaria
Pruritus
Thyroid gland enlargement
Retrograde amnesia
Nausea
Vomiting
Peripheral neuropathy
Optic neuritis
Stomach pain
Weakness
Visual impairment
Optic atrophy
Abdominal cramps
Itching of rectal area
Mechanism of Action
Acts primarily in intestinal lumen; mechanism unknown