Hydrocortisone rectal

Ulcerative Proctitis

Ulcerative Proctitis Application to distal rectum in patients who cannot retain steroid enemas Foam 1 applicatorful PR once daily or q12hr for 2-3 weeks, then every other day if necessary; use lowest dosage that maintains clinical response; discontinue if no proctologic improvement is noted after 2-3 weeks 1 applicatorful = 900 mg; contains 90 mg hydrocortisone acetate (= 80 mg hydrocortisone) Suspension 1 enema at bedtime for 21 days or until remission is achieved; 2-3 months of therapy may be required; taper to discontinue long-term therapy; improvement in mucosal integrity may be preceded by clinical improvement

Documented hypersensitivity Systemic fungal infections Ileostomy during immediate or early postoperative period Obstruction, abscess, perforation, peritonitis, fresh intestinal anastomoses, extensive fistulas

Always follow directions for use on product carton Do not insert any part of aerosol container directly into anus Sigmoidoscopy is recommended for judging treatment course, rather than symptomatic improvement

C Pregnancy category: C Lactation: Use with caution

Frequency Not Defined Burning Dryness Folliculitis Hypopigmentation Itching Pain Rectal bleeding Secondary infection

Decreases inflammation by suppressing migration of polymorphonuclear leukocytes (PMNs) and reversing increased capillary permeability