Framycetin sulfate (Dressing)

Indications

Wounds dressings, Thermal: Light, and not too extensive, burns or scalds. Traumatic: Lacerations, abrasions, bites, wounds, crash injuries. Miscellaneous: Secondary infected skin condition, (eg, eczema, dermatitis, herpes zoster).

Adult Dose

Apply a single layer on the lesion & cover w/ a suitable dressing. For wounds w/ profuse exudate change the dressing once daily.

Contra Indications

Known allergy to lanolin or framycetin, or where organisms are known to be resistant to framycetin.

Precautions

Allergy to Streptomyces-derived antibiotics. Large-scale burns.

Pregnancy-Lactation

C

Interactions

Co-admin of gramicidin with framycetin reduces the risk of selecting resistant bacteria.

Adverse Effects

Possible ototoxicity Open wounds, large areas, renal impairment on prolonged use.

Mechanism of Action

Framycetin is an aminoglyoside antibiotic which is the major component of neomycin. Susceptible organisms include many gram-negative bacteria (but not Pseudomonas) and many strains of Staphylococcus. Used topically in the treatment of skin, eye and ear infections often in combination with steroids and other antimicrobials.