Etamsylate
Indications
Menorrhagia, Control of haemorrhage after surgery
Adult Dose
Oral
Menorrhagia
Adult: 500 mg 4 times daily during menstruation.
Oral
Control of haemorrhage after surgery
Adult: 250-500 mg every 4-6 hr as needed. May also be given via IV/IM inj.
Child Dose
Parenteral
Treatment and prophylaxis of periventricular haemorrhage in low birth-weight neonates
Child: Low birth-weight neonate: 12.5 mg/kg IM/IV Inj every 4-6 hr.
Administration
May be taken with or without food. May be taken w/ meals to minimise GI upset.
Contra Indications
Hypersensitivity. Porphyria. Pregnancy and lactation.
Pregnancy-Lactation
Not Classi
Adverse Effects
Headache, skin rash, nausea. IV: Transient hypotension.
Mechanism of Action
Ethamsylate stops haemorrhage from small blood vessels by stabilising the capillary wall and correcting abnormal platelet adhesion.