Carbonyl Iron

Indications

Dietary supplement, Iron deficiencies, Iron deficiency anemia

Adult Dose

Oral One capsule daily. In more severe cases, 2 capsules a day may be required

Child Dose

Oral >12 years old: One capsule daily. Severe Iron Deficiency Anemia 4-6 mg/kg PO divided q8hr Mild to Moderate Iron Deficiency Anemia 3 mg/kg PO qDay or divided q12hr Prophylaxis 1-2 mg/kg PO; 15 mg PO maximum

Administration

For maximum absorption take on empty stomach, but may take with or after meals to minimize GI irritation

Contra Indications

This product is contraindicated in patients with a known hypersensitivity to any of the ingredients.

Precautions

Do not take within 2 hr of oral tetracycline antibiotics Not for use in patients receiving frequent blood transfusions Avoid in premature infants until their deficient vitamin E stores at birth are replenished May cause increased red cell hemolysis & hemolytic anemia in infants with low serum vitamin E concentrations Ask healthcare professional if it is safe to use if do not have an iron deficiency; this drug is generally not for use by people who have a normal iron balance Tablet dosage form may contain lactose; ask healthcare professional if lactose intolerant or milk allergy Dose needs may be different during pregnancy or while breastfeeding Not for use >6 months unless prescribed by healthcare professional or in patients with continuous bleeding or menorrhagia Keep out of reach of children; accidental overdose can be fatal Severe iron toxicity may occur in overdose, especially when ingested by children Nonintentional iron overdose is leading cause of fatal poisoning in children <6 years; keep out of reach of children

Pregnancy-Lactation

Not Classi Pregnancy Category: Not available Lactation: Excreted in breast milk

Interactions

Antacids may decrease the absorption of carbonyl iron. Contraindicated (0) Serious (14) baloxavir marboxil ciprofloxacin demeclocycline doxycycline eltrombopag fleroxacin gemifloxacin levofloxacin minocycline moxifloxacin mycophenolate ofloxacin oxytetracycline tetracycline

Adverse Effects

>10% Constipation,Diarrhea,Nausea,Epigastric pain,Dark stools,Vomiting Frequency Not Defined Hemosiderosis (during long-term administration of large amounts),Urine discoloration,Dental stain by some formulations,Heartburn

Mechanism of Action

Iron: Essential component in the formation of hemoglobin; adequate amounts of iron are necessary for effective erythropoiesis; also serves as a cofactor of several essential enzymes, including cytochromes that are involved in electron transport. Replacement of iron stores found in hemoglobin, myoglobin, and enzymes; works to transport oxygen via hemoglobin.

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