Betamethasone 0.1% + Fusidic Acid 2% Topical
Indications
Lichen planus, Psoriasis, Eczema, Contact dermatitis, Seborrhoeic dermatitis, Systemic lupus erythematosus, Lichen simplex, Prurigo nodularis, Sunburns
Adult Dose
Adult: Topical As cream: Apply twice daily. Usual duration: Up to 2 wk/course.
Contra Indications
Skin lesions of viral, fungal or bacterial origin, acne rosacea and perioral dermatitis.
Precautions
Avoid prolonged continuous treatment especially in infants and children. Extended treatment may increase the risk of contact sensitisation and development of antibiotic resistance. Not to be used for >7 days if there is no clinical improvement. Increased risk of glaucoma if preparation enters the eye(s). Pregnancy and lactation.
Pregnancy-Lactation
Not Classi
Adverse Effects
Prolonged intensive treatment may cause local atrophic changes in the skin e.g. striae, thining and dilatation of superficial blood vessels. Dryness, itching, irritation, hypopigmentation, burning sensation at the site of application or miliaria.
Mechanism of Action
Betamethasone valerate is a topical corticosteroid that is effective in inflammatory dermatoses. Topical fusidic acid is effective against Staphyloccus aureus, Streptococci, Corynebacteria, Neisseria and some Clostridia and bacteroides. Antibacterial activity of fusidic acid is not reduced when used with betamethasone.