Beclomethasone + Salicyclic Acid Topical
Indications
Inflammatory skin conditions; Hyperkeratotic and scaling skin conditions; Corticosteroid-responsive dermatoses
Adult Dose
Topical/Cutaneous
Inflammatory skin conditions; Hyperkeratotic and scaling skin conditions; Corticosteroid-responsive dermatoses
Apply to the affected area 1-2 times daily for 2 wk.
Contra Indications
Viral skin infections (e.g. vaccinia, varicella and herpes simplex), TB, acne, rosacea, napkin eruptions, fungal or bacterial skin infections w/o suitable concomitant anti-infective therapy, perioral dermatitis, ulcerative conditions, perianal and genital pruritus.
Precautions
Absorption of corticosteroid through the skin is increased when used w/ occlusive dressings. Avoid long term continuous therapy. Childn. Pregnancy and lactation. Patient Counselling Avoid contact w/ the eyes and mucous membranes.
Pregnancy-Lactation
Not Classi
Adverse Effects
Irritation, burning, itching, dryness, folliculitis, maceration of skin, skin atrophy, hypertrichosis, acneiform eruptions, secondary infection, hypopigmentation, perioral dermatitis, allergic contact dermatitis, striae and miliaria.
Mechanism of Action
Beclometasone controls the rate of protein synthesis, depresses the migration of polymorphonuclear leukocytes, fibroblasts, reverses capillary permeability and lysosomal stabilisation at the cellular level to prevent or control inflammation.
Salicylic acid has keratolytic action. It softens keratin, loosens cornified epithelium and desquamates the epidermis. It aids in the penetration of beclomethasone.