Beclomethasone + Miconazole Topical
Indications
Dermatoses where secondary bacterial and candidal infection present.
Adult Dose
Topical/Cutaneous
Corticosteroid-responsive dermatoses
Adult: Apply cream/ointment onto affected area bid or tid.
Contra Indications
Hypersensitivity.
Precautions
Children, elderly; pregnancy and lactation.
Pregnancy-Lactation
Not Classi
Adverse Effects
Loss of skin collagen and SC atrophy; local hypopigmentation of deeply pigmented skin; local irritation, burning, contact dermatitis
Mechanism of Action
Beclometasone controls the rate of protein synthesis, depresses the migration of polymorphonuclear leukocytes, fibroblasts, reverses capillary permeability and lysosomal stabilisation at the cellular level to prevent or control inflammation.
Miconazole inhibits ergosterol synthesis thus damaging fungal cell wall membrane and increases its permeability, allowing leakage of nutrients.