Beclomethasone + Miconazole Topical

Indications

Dermatoses where secondary bacterial and candidal infection present.

Adult Dose

Topical/Cutaneous Corticosteroid-responsive dermatoses Adult: Apply cream/ointment onto affected area bid or tid.

Contra Indications

Hypersensitivity.

Precautions

Children, elderly; pregnancy and lactation.

Pregnancy-Lactation

Not Classi

Adverse Effects

Loss of skin collagen and SC atrophy; local hypopigmentation of deeply pigmented skin; local irritation, burning, contact dermatitis

Mechanism of Action

Beclometasone controls the rate of protein synthesis, depresses the migration of polymorphonuclear leukocytes, fibroblasts, reverses capillary permeability and lysosomal stabilisation at the cellular level to prevent or control inflammation. Miconazole inhibits ergosterol synthesis thus damaging fungal cell wall membrane and increases its permeability, allowing leakage of nutrients.

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