Allium cepa + Heparin + Allantoin
Indications
Antiscar gel is indicated for the following scar treatment:
hypertrophic and keloid scars
scar that occurs after surgery
scar that occurs after amputation, burns and trauma
scar due to traumatic tendon contracture
Adult Dose
Antiscar Gel should be applied 3-4 times a day to the a ected area and massage gently
in order to achieve better penetration. Continue with a circular motion until the gel is
completely absorbed. Treatment may take several weeks or months depending on size of
existing scars and contracture.
Contra Indications
Antiscar Gel should not be used in patients with known hypersensitivity to any of its ingredients.
Precautions
During treatment of fresh scars with this preparation, excess cold, UV lights and abrupt
massage should be avoided. Avoid contact with eyes, the inside of the nose or mouth and
other mucous membranes.
Pregnancy-Lactation
There are no studies conducted during pregnancy and lactation periods. Therefore it should be used with caution.
Interactions
There is no known and reported drug interaction.
Adverse Effects
Antiscar Gel is generally well tolerated even on long term use. In rare cases some local
irritations are reported such as slight erythema and itching. These side e ects do not
require discontinuation of the treatment.
Mechanism of Action
Extract of Allium cepa- It is derived from the membrane of Allium cepa (onion membrane). It shows antiphlogistic eects through inhibition of inammatory mediators’ secretion and anti-allergenic eect. Extract of Allium cepa inhibits growth of broblast of dierent origin, particularly kelloidal broblasts. It has also bactericidal eect. While these properties stimulate primary wound healing, it prevents non-physiological scar formation. Heparin- In case of local application, it shows inhibitory eect on broblast proliferation. While heparin increases tissue hydration, it reduces irritation resulted from induration and inammation. Allantoin- Allantoin stimulates cellular proliferation. It also supports the development of healthy cells. Allantoin is convenient substance for the treatment of scar through its properties of stimulating epithelization and providing elastic surface formation.