Adrenochrome Monosemicarbazone
Indications
Capillary bleeding, Haemoptysis, Haematuria, Retinal hemorrhage,Se condary hemorrhage, Menorrhagia.
Adult Dose
Oral As a haemostatic
Adult: 10-30 mg tid.
Injection As a haemostatic Adult: 10 mg daily by SC/IM inj.
Alternatively, 25-100 mg daily by IV Inj or drip infusion.
Pre-operative: 2-6ml at suitable intervals.
Post-operative: 1-2ml every 2hrs.
Non-surgical: 2-4ml tid.
Child Dose
Child <6yrs: 1-2ml tid.
Contra Indications
Should not be administered to patients with hypersensitivity.
Precautions
Because of the content of diprophylline (90 mg/ml), the dosage to premature babies, infants and young children should not exceed 0.3 ml.
Pregnancy-Lactation
Not Classi
Interactions
No specific drug interaction has been demonstrated.
Adverse Effects
Allergic reactions may occur like dyspnoea, bronchospasm, skin reaction etc
Mechanism of Action
Carbazochrome is an oxidation product of adrenaline (epinephrine). It has been used as a haemostatic agent.