Duphaston Tablet

Endometriosis, Miscarriage, Menstrual disorders, Infertility, Dysmenorrhea, Dysfunctional uterine bleeding, Premenstrual syndrome, Hormone replacement therapy

Oral Endometriosis Adult: 10 mg bid-tid cyclically or continuously. Recurrent miscarriage Adult: 10 mg bid given cyclically until conception, then continuously until wk 20 of pregnancy, after which dose may be gradually reduced. Menstrual disorders Adult: 10 mg bid in a cyclical regimen. Threatened miscarriage Adult: Initially, 40 mg followed by 10 mg or more every 8 hr, continued for a wk after symptoms are relieved. Reduce dose gradually after that unless symptoms return. Infertility Adult: 10 mg bid. Endometrial protection during menopausal hormonal replacement therapy Adult: 10 mg 1-2 times daily in a cyclical regimen or 5 mg daily.

May be taken with or without food.

Hypersensitivity; pregnancy. Undiagnosed abnormal vag bleeding, thromboembolic disorders, history or existing cerebrovascular or coronary artery disease, missed or incomplete abortion, known or suspected carcinoma of the breast or genital organs, severe hepatic dysfunction, as a diagnostic test for pregnancy.

Monitor closely for loss of vision, proptosis, diplopia, migraine, signs and symptoms of embolic disorders. CVD or renal impairment, epilepsy, asthma, other conditions which may be aggravated by fluid retention. Lactation.

Not Classi

Carbamazepine, griseofulvin, phenobarbital, rifampicin enhances the clearance of progestogens.

Dizziness, nausea, headache, fatigue, emotional lability, irritability; abdominal pain and distention; muskuloskeletal pain.

Dydrogesterone is a progestogen structurally related to progesterone. However, unlike progesterone, it does not induce an increase in temp nor inhibit ovulation and may be preferred over other progestational agents when contraceptive effect is not required. It does not have oestrogenic or androgenic properties.

Duphaston 10mg Tablet manufactured by Solvay Pharmaceuticals,Netherlands. Its generic name is Dydrogesterone.