Tritanrix HB Injection

Diphtheria, Tetanus, Pertussis, Hepatitis B in infants

Immunization Diphtheria, tetanus, pertussis, hepatitis B Deep IM inj Primary vaccination 3 doses of 0.5 mL w/in the 1st 6 mth of life at intervals of at least 4 wk. Booster dose: Administer during the 2nd yr of life.

Previous encephalopathy after pertussis vaccine; acute severe febrie illness.Hypersensitivity to any component of the vaccine. Childn w/ history of encephalopathy of unknown etiology occurring w/in 7 days following previous vaccination. Do not administer IV.

Previous reaction to DTP vaccine; family history of convulsions, SIDS; bleeding dis­orders; immunosuppression /deficiency; preg­nancy, lactation. Postpone vaccination in patients w/ acute severe febrile illness. Should be administered SC in patients w/ thrombocytopenia or bleeding disorders. Syncope, risk of apnea. Temp >40°C, persistent crying lasting >3 hr & collapse or shock-like state w/in 48 hrs; convulsions w/ or w/o fever w/in 3 days. High incidence of pertussis. Childn w/ progressive neurological disorders including infantile spasms, uncontrolled epilepsy or progressive encephalopathy. Consider potential risk of apnea & need for resp monitoring for 48-72 hr to very premature infants (>28 wk of gestation) particularly those w/ previous history of resp immaturity. Lactation: Not indicated for women of childbearing age

C Pregnancy Category: C Lactation: Not indicated for women of childbearing age

>10% Irritability/fussiness (61-65%),Drowsiness (41-57%),Fever (28-39%),Loss of appetite (26-31%),Swelling (17-29%) 1-10% Fever (≤1%) <1% Anorexia,Apnea,Erythema,Decreased consciousness,Diarrhea,Hypotonia,Encephalitis,Brachial neuritis,Erythema,Peripheral neuropathy,Cough,Lethargy,Limb pain,Liver function test abnormalities,Rash,Restlessness

Vaccine is used for the active immunisation of diphtheria, tetanus and pertussis in children from 6 wk to 6 yr of age. Production of specific antibodies to tetanus, diphtheria, and pertusis (active immunity). Conveys active immunity via stimulation of production of endogenously produced antibodies

Tritanrix HB Injection manufactured by Glaxo SmithKline Biological S.A.,Belgium. Its generic name is Diphtheria Toxoid 30IU + Tetanus Toxoid 60IU + Pertusis + Hepatitis B (Vaccine).