Ipramid Respirator Solution Solution
Ipratropium Bromide
250mcg/ml
Beximco Pharmaceuticals Ltd.
| Pack size | |
|---|---|
| Retail Price | 32.00 |
Indications
Asthma, chronic obstructive pulmonary disease, chronic bronchitis, emphysema.
Adult Dose
Inhalation
Asthma; Chronic obstructive pulmonary disease
Adult: As Inhaler: Adults: 1-2 puffs (20 mg/puff) 3-4 times daily. Single doses of up to 80 mcg may be required in some patients.
As nebulized soln
250-500 mcg 3-4 times daily.
Child Dose
Inhalation
Asthma; Chronic obstructive pulmonary disease
Child: As metered-dose aerosol:
<6 yr 20 mcg tid;
6-12 yr 20-40 mcg tid.
As soln for nebulisation:
<6 yr For acute asthma: 125-250 mcg, given no more often than 6 hrly up to a total dose of 1 mg.
6-12 yr For acute and chronic asthma: 250 mcg, repeated as necessary up to a total dose of 1 mg.
Contra Indications
Ipratropium Bromide solution should not be taken by patients with known hypersensitivity to atropine or its derivatives or to any other component of the product.
Precautions
Bladder neck obstruction, narrow-angle glaucoma or patients susceptible to glaucoma, prostatic hyperplasia. Protect patient's eyes from nebulised drug. Renal and hepatic impairment. Pregnancy, lactation, children, elderly.
Pregnancy-Lactation
B
Pregnancy category: B
Lactation: Unknown whether drug is excreted in breast milk
Interactions
Increased toxicity with other anticholinergic drugs.
Adverse Effects
Dry mouth, urinary retention, buccal ulceration, paralytic ileus, headache, nausea, constipation, paradoxical bronchospasm, immediate hypersensitivity reactions (urticaria, angioedema), acute angle-closure glaucoma.
Potentially Fatal: Anaphylactic reactions, atrial fibrillation, supraventricular tachycardia.
Mechanism of Action
Ipratropium bromide blocks the action of acetylcholine at parasympathetic sites in bronchial smooth muscle causing bronchodilation.
Note
Ipramid Respirator Solution 250mcg/ml Solution manufactured by Beximco Pharmaceuticals Ltd.. Its generic name is Ipratropium Bromide.