Cilnior Tablet
Cilnidipine
5 mg
Orion Pharma Ltd.
| Pack size | 30's |
|---|---|
| Retail Price | 7.00 |
Indications
Hypertension
Adult Dose
Oral
Hypertension
Adult: 5-10 mg once daily, increase to 20 mg once daily if necessary.
Contra Indications
Cardiogenic shock; recent MI or acute unstable angina; severe aortic stenosis, heart failure.
Cilnidipine is contraindicated in patients with known sensitivity to Cilnidipine or any of the excipients.
Precautions
Hypotension, poor cardiac reserve, heart failure. Sudden withdrawal may exacerbate angina. During the discontinuation, the dosage should be gradually decreased under close observation.
Discontinue in patients who experience ischemic pain following administration. Pregnancy, lactation.
Pregnancy-Lactation
Not Classi
Cilnidipine should not be administered in pregnant woman or woman having possibilities of being pregnant. It is also advisable to avoid the administration of Cilnidipine to nursing mothers. However, if the administration is indispensable, the patient should be instructed to discontinue lactation.
Interactions
Other antihypertensives; aldesleukin; antipsychotics that cause hypotension; may modify insulin and glucose responses; quinidine; carbamazepine; phenytoin; rifampicin; cimetidine; erythromycin.
Adverse Effects
Dizziness; flushing; headache; hypotension; peripheral oedema; tachycardia; palpitations; GI disturbances; increased micturition frequency; lethargy; eye pain; depression; ischaemic chest pain; cerebral or myocardial ischaemia; transient blindness; rashes; fever; abnormal liver function; gingival hyperplasia; myalgia; tremor; impotence.
Mechanism of Action
Cilnidipine is a dihydropyridine calcium-channel blocker. It inhibits cellular influx of calcium, thus causing vasodilatation. It has greater selectivity for vascular smooth muscle. It has little or no action at the SA or AV nodes and -ve inotropic activity is rarely seen at therapeutic doses.
Note
Cilnior 5 mg Tablet manufactured by Orion Pharma Ltd.. Its generic name is Cilnidipine.