Busper Tablet

Anxiety

Anxiety Disorders Initial Dose: 10-15 mg per day, taken orally, divided every 8-12 hours. Dose Adjustment: Increase by 5 mg/day every 2-3 days. Maintenance Dose: 15-30 mg per day, divided every 8-12 hours. Maximum Dose: Do not exceed 60 mg per day.

Renal impairment: Not recommended for patients with severe impairment

Hepatic impairment: Not recommended for patients with severe impairment

May be taken with or without food. Take consistently either always w/ or always w/o meals.

Hypersensitivity. Epilepsy; severe renal or hepatic impairment; children <18 yr; pregnancy, lactation.

Do not use PRN for anxiety Will not prevent withdrawal from other anxiolytics, such as benzodiazepine May cause cognitive motor impairment Restlessness syndrome associated with therapy Use in severe renal/hepatic impairment not recommended Use with MAO inhibitors may result in hypertensive reaction (use not recommended)

B Pregnancy category: B Lactation: Excretion in milk unknown/not recommended

Enhanced sedative effects with alcohol or CNS depressants. Increases serum haloperidol. Concurrent admin with MAOIs may lead to increase in BP. Potentially Fatal: Elevation of BP when taken concomitantly with MAOIs. Contraindicated (6) isocarboxazid linezolid phenelzine procarbazine selegiline transdermal tranylcypromine

>10% Dizziness (12%) 1-10% Drowsiness (10%),Nausea (8%),Headache (6%),Nervousness (5%),Blurred vision (2%),Confusion (2%),Diarrhea (2%),Excitement (2%),Insomnia (2%),Myalgia (1%),Numbness (2%),Paresthesia (1%),Rash (1%),Tremor (1%),Weakness (2%),Nasal congestion (1%),Sore throat (1%),Nonspecific chest pain (1%),Tinnitus (1%),Dream disturbances (1%) <1% Akathisia,Allergic reaction,Anorexia,Bruising,Galactorrhea,Heart failure,Menstrual irregularity,Suicidal ideation,Syncope,Alopecia,Eosinophilia,Edema,Enuresis,Increased ocular pressure,Visual disturbances,Rectal bleeding,Photophobia,Dystonia

Buspirone exerts anxiolytic activity through high affinity for serotonin 5-HT1A and 5-HT2 receptors. It has moderate affinity for dopamine D2-receptors but no affinity for GABA receptors.

Busper 5mg Tablet manufactured by Kumudini Pharma Ltd.. Its generic name is Buspirone.