Ontab Tablet
Bromelain +Trypsin
50 mg+ 1 mg
Neoventis Biotech Herbal & Nutraceuticals
| Pack size | 50's pack |
|---|---|
| Retail Price | 13.00 |
Indications
Ontab is indicated for inflammatory pains, soft tissue inflammation, edema associated with trauma and surgery such as in gynecological conditions, breast engorgement, fractures, sprains, injuries, hemorrhoid, anal prolapsed.
Adult Dose
Initially 2 tabs 3 times daily. Maintenance 1 tab 3 times daily preferably before meals
Contra Indications
Hypersensitivity.
Precautions
Allergies: If you are allergic to pineapple, latex, wheat, celery, papain, carrot, fennel, cypress pollen, or grass pollen, you might have an allergic reaction to bromelain.
Surgery: Bromelain might increase the risk of bleeding during and after surgery. Stop using bromelain at least 2 weeks before a scheduled surgery.
Pregnancy-Lactation
Pregnancy Category-Not Classified. FDA has not yet classified the drug into a specified pregnancy category.
Interactions
There are no known drug interactions and none well documented.
Adverse Effects
Trypsin seems to be safe when used by healthcare professionals for wound cleaning and healing. It can cause side effects such as pain and burning. Not enough is known about the safety of trypsin for its other uses.
Mechanism of Action
Bromelain acts through multiple pathways, including anti-inflammatory effects by modulating prostaglandins and reducing bradykinin levels, fibrinolytic activity which breaks down fibrin, and immunomodulatory effects by influencing immune cells and cytokines. Trypsin acts by hydrolyzing (breaking) peptide bonds in proteins, specifically at the carboxyl side of the amino acids lysine and arginine, using a catalytic triad of serine, histidine, and aspartate to form an acyl-enzyme intermediate.
Note
Ontab 50 mg+ 1 mg Tablet manufactured by Neoventis Biotech Herbal & Nutraceuticals. Its generic name is Bromelain +Trypsin.