Obstane Cream

Chlorhexidine Gluconate 1 % Oral prep
1%
Greenland Pharmaceuticals Ltd.
Pack size60 ml
Retail Price90.00

Indications

Dental and gum infection.

Adult Dose

Adult: As cream/gel: Apply to the affected area 2-3 times daily or as directed by physician.

Contra Indications

Hypersensitivity.

Precautions

Avoid eating, drinking, or brushing your teeth just after using this medicationAvoid contact w/ eyes. Do not inject or use in body cavities.

Pregnancy-Lactation

B

Interactions

Soaps, other anionic agents, borates, bicarbonates, carbonates, chlorides, citrates, nitrates, phosphates & sulfates.

Adverse Effects

Local irritation. Chlorhexidine gluconate can stain teeth, dentures, tooth restorations, your tongue, or the inside of your mouth.

Mechanism of Action

Chlorhexidine is a very potent cationic chemoprophylactic agent that has a broad-spectrum of activity against gm+ve and gm-ve bacteria. It is both bacteriostatic and bactericidal depending on its concentration. The bactericidal effect, which is achieved at high concentrations, is due to the binding of the cationic to negatively charged bacterial cell walls and extramicrobial complexes. Bacteriostatic effect is achieved at low concentrations which causes an alteration of bacterial cell osmotic equilibrium and leakage of potassium and phosphorus.

Note

Obstane 1% Cream manufactured by Greenland Pharmaceuticals Ltd.. Its generic name is Chlorhexidine Gluconate 1 % Oral prep.