Stilamin Injection

Somatostatin
3mg/amp
Merck Serono S.A., Switzerland
Pack size1 amps pack
Retail Price5085.00

Indications

GI haemorrhage

Adult Dose

Intravenous Gastrointestinal haemorrhage Adult: Initially, 250 mcg as a bolus inj over 3-5 min, followed by a continuous infusion of 3.5 mcg/kg/hr until bleeding has ceased. May continue for a further 48-72 hr to prevent recurrent bleeding.

Precautions

Monitor blood glucose levels. May inhibit intestinal absorption thus concomitant parenteral nutrition may be recommended.

Pregnancy-Lactation

B

Interactions

Lengthens the time of hexobarbital-induced sleep & potentiates the action of pentetrazol.

Adverse Effects

Rapid infusion may lead to abdominal discomfort, nausea, flushing, bradycardia.

Mechanism of Action

Somatostatin is a polypetide obtained synthetically or from the hypothalamus. It acts by inhibiting the release of growth hormone from the anterior pituitary. It also inhibits the release of thyrotrophin and corticotropin from the pituitary, glucagon and insulin from the pancreas. It also regulates duodenal and gastric secretions. It may also play a role in pain perception.

Note

Stilamin 3mg/amp Injection manufactured by Merck Serono S.A., Switzerland. Its generic name is Somatostatin.

Some other brands of Somatostatin