Helmisole Tablet
Levamisole
40mg
G. A. Company Ltd.
| Pack size | 100's pack |
|---|---|
| Retail Price | 0.41 |
Indications
Ascariasis, Ancylostomiasis
Adult Dose
Oral
Ascariasis
Adult: 150 mg as a single dose.
Mixed ascariasis-hookworm infections; Ancylostomiasis
Adult: 2.5 mg/kg as a single dose, repeated after 7 days in severe cases.
Child Dose
Oral
Ascariasis
Child: 3 mg/kg as a single dose.
Mixed ascariasis-hookworm infections; Ancylostomiasis
Child: 2.5 mg/kg as a single dose, repeated after 7 days in severe cases.
Administration
Should be taken with food. Take w/ meals to minimise side effects eg nausea.
Contra Indications
Preexisting blood disorders; pregnancy and lactation; rheumatoid arthritis; severe renal impairment.
Precautions
Hepatic impairment, Sjogren's syndrome.
Pregnancy-Lactation
C
Interactions
May increase toxicity of phenytoin. Increases bioavailability of ivermectin; decreases bioavailability of albendazole. Alcohol causes disulfiram-like reaction.
Adverse Effects
Nausea, vomiting, diarrhoea, abdominal pain, dizziness and headache. Fever, influenza-like syndrome, arthralgia, muscle pain, rash, taste disturbances and cutaneous vasculitis.
Potentially Fatal: Agranulocytosis, leucopenia, thrombocytopenia.
Mechanism of Action
Levamisole is the active laevo-isomer of tetramisole. It works by paralysing susceptible intestinal worms which are then excreted from the intestines. Levamisole also enhances cellular immune responses in humans.
Note
Helmisole 40mg Tablet manufactured by G. A. Company Ltd.. Its generic name is Levamisole.