Gastrodyne Suspension

Aluminium Oxide + Magnesium Hydroxide
175 mg + 225 mg/5 ml
Orion Pharma Ltd.
Pack size200ml bot
Retail Price72.00

Indications

Hyperacidity, Flatulence, Gastric ulcer, Duodenal ulcer, Gastritis, Stomach distension

Adult Dose

Chew 1-2 tablets after meals and at bedtime as needed (up to 4 times a day). Do not take more than 16 tablets in 24 hours

Administration

After meals and at bedtime as needed. For best results, drink a half glass of water or other liquid after each dose.

Contra Indications

Hypophosphataemia.

Precautions

Renal dysfunction, low phosphate diet, prolonged use.

Pregnancy-Lactation

Not Classi

Interactions

Aluminium Hydroxide: Enhanced absorption with citrates or ascorbic acid. Decreases absorption of allopurinol, tetracyclines, quinolones, cephalosporins, biphosphonate derivatives, corticosteroids, cyclosporin, delavirdine, Fe salts, imidazole antifungals, isoniazid, mycophenolate, penicillamine, phosphate supplements, phenytoin, phenothiazines, trientine. Magnesium Hydroxide: Decreases absorption of tetracyclines and biphosphonates. Separate administration of these and other drugs by around 2 hr.

Adverse Effects

Diarrhoea, constipation, nausea, vomiting.

Mechanism of Action

Alumunium hydroxide acts on the HCl in the stomach by neutralization, forming aluminium chloride salt and water. Magnesium hydroxide increases peristaltic activity causing osmotic retention of fluids, thus resulting in bowel evacuation. It also reduces stomach acid by reacting with hydrochloric acid to form Mg chloride.

Note

Gastrodyne 175 mg + 225 mg/5 ml Suspension manufactured by Orion Pharma Ltd.. Its generic name is Aluminium Oxide + Magnesium Hydroxide.

Some other brands of Aluminium Oxide + Magnesium Hydroxide