Survanta Intratracheal suspension

Phospholipids
25mg/ml
Marketed By Unimed & Unihealth Manufacturers Ltd (Abbott Pharma Product)
Pack size8ml vial
Retail Price42000.00

Indications

Resp distress syndrome (RDS) in premature infants.

Child Dose

Prevention in premature infant <1250 g birthwt or w/ evidence of surfactant deficiency Preferably w/in 15 mins of birth. Rescue Preferably by 8 hr of age. 4 mL/kg birth wt(100 mg of phospholipids/kg birth wt) intratracheally up to 4 doses in 1st 48 hr. Doses should not be given more frequently than 6 hrly. To be administered as soon as possible.

Contra Indications

None known.

Precautions

Infants <600 g birth wt. For intratracheal use only.

Pregnancy-Lactation

Not Classi

Adverse Effects

Transient bradycardia. O2 desaturation, endotracheal tube reflux & blockage, pallor, vasoconstriction, hypotension, HTN, hypocarbia, hypercarbia & apnea.

Mechanism of Action

Natural bovine pulmonary surfactant; replaces deficient endogenous lung surfactant in neonates with respiratory distress syndrome. Surfactant prevents the alveoli from collapsing during expiration by lowering surface tension between alveolar surfaces and air.

Note

Survanta 25mg/ml Intratracheal suspension manufactured by Marketed By Unimed & Unihealth Manufacturers Ltd (Abbott Pharma Product). Its generic name is Phospholipids.