Ancid Plus Suspension

Aluminium Hydroxide + Magnesium Hydroxide
200 mg + 400 mg + 30 mg/5
Renata PLC.
Pack size200ml bot
Retail Price46

Indications

Heartburn, Reflux oesophagitis, Hyperacidity, Peptic ulcer, Constipation, Indigestion

Adult Dose

Adult: PO Gastric Hyperacidity, Heartburn: Up to 1 g/day. Hyperphosphataemia in chronic renal failure Up to 10 g/day in divided doses w/ meals. 10-20 mL PO between meals & qHS

Administration

May be taken with or without food.

Contra Indications

Hypersensitivity to aluminium salts.

Precautions

Chronic renal impairment; CHF; oedema; cirrhosis and low Na diets; patients with recent GI haemorrhage. Administer 2-3 hrs before/after another medication to minimise drug interactions. Pregnancy and lactation. Lactation: excretion in milk unknown; use caution

Pregnancy-Lactation

C Pregnancy Category: C Lactation: excretion in milk unknown; use caution

Interactions

Aluminium Hydroxide: Enhanced absorption with citrates or ascorbic acid. Decreases absorption of allopurinol, tetracyclines, quinolones, cephalosporins, biphosphonate derivatives, corticosteroids, cyclosporin, delavirdine, Fe salts, imidazole antifungals, isoniazid, mycophenolate, penicillamine, phosphate supplements, phenytoin, phenothiazines, trientine. Magnesium Hydroxide: Decreases absorption of tetracyclines and biphosphonates. Separate administration of these and other drugs by around 2 hr.

Adverse Effects

>10% Aluminum oxide,Chalky taste,Constipation,Fecal impaction,Stomach cramps Frequency Not Defined Aluminum oxide,Nausea,Vomiting,Aluminum intoxication,Hypophosphatemia,Osteomalacia,Magnesium oxide,Diarrhea,Hypermagnesemia

Mechanism of Action

Alumunium hydroxide acts on the HCl in the stomach by neutralization, forming aluminium chloride salt and water. Magnesium hydroxide increases peristaltic activity causing osmotic retention of fluids, thus resulting in bowel evacuation. It also reduces stomach acid by reacting with hydrochloric acid to form Mg chloride.

Note

Ancid Plus 200 mg + 400 mg + 30 mg/5 Suspension manufactured by Renata PLC.. Its generic name is Aluminium Hydroxide + Magnesium Hydroxide.

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