Dro SPA Tablet

Drotaverine Hydrochloride
40mg
Pharmik Laboratories Ltd.
Pack size200's Pack
Retail Price1.00

Indications

Gastrointestinal tract spasm, Irritable bowel syndrome, Dysmenorrhea, Biliary colics, Renal colics

Adult Dose

Oral As an antispasmodic Adult: 1 to 2 tablets, 3 times daily. Injection: Adults: 1 to 2 ampoules, intramuscularly or subcutaneously, 1-3 times daily. For the management of acute stone colics: 1 or 2 ampoules by slow intravenous injection.

Child Dose

Oral As an antispasmodic Children (over 6 years): 1/2 to 1 tablet, 1-2 times daily. 40 mg 1-2 times daily Children (1-6 years): 1/4 to 1/2 tablet, 1-2 times daily. 20 mg 1-2 times daily

Administration

May be taken with or without food.

Contra Indications

Severe renal/hepatic/cardiac dysfunction. Porphyria.

Precautions

Exercise caution in patients with renal/hepatic/cardiac dysfunction. Pregnacy, lactation.

Pregnancy-Lactation

C

Interactions

May attenuate the action of levodopa. Concurrent use of analgesics, antimuscarinics or benzodiazepines. Additive beneficial effect with concurrent use of analgesics, antimuscarinics or benzodiazepines.

Adverse Effects

Vertigo, nausea, vomiting, dry mouth.

Mechanism of Action

Drotaverine has antispasmodic effect mediated via inhibition of phosphodiesterase-IV, specific for smooth muscle. It has a rapid and direct action on the smooth muscle. It acts to correct cyclic AMP and Ca imbalance at the spastic site, thereby relieving smooth muscle spasm and pain.

Note

Dro SPA 40mg Tablet manufactured by Pharmik Laboratories Ltd.. Its generic name is Drotaverine Hydrochloride.

Some other brands of Drotaverine Hydrochloride