Nopik 120 Tablet
Nateglinide
120mg
Square Pharmaceuticals PLC.
| Pack size | 30's Pack |
|---|---|
| Retail Price | 80.00 |
Indications
Type 2 DM
Adult Dose
Oral
Type 2 diabetes mellitus
Adult: 60 or 120 mg tid.
Administration
Take immediately before or up to ½ hr before meals.
Contra Indications
Diabetic ketoacidosis; IDDM. Lactation.
Precautions
Geriatric patients, debilitated and malnourished patients; adrenal or pituitary insufficiency, moderate to severe hepatic impairment; severe renal impairment. Monitor glycaemic levels during periods of stress. Pregnancy.
Lactation: unsafe
Pregnancy-Lactation
C
Pregnancy Category: C
Lactation: unsafe
Interactions
Increased levels/effects with enzyme inhibitors (e.g. fluconazole). Increased hypoglycaemic effects with salicylates, MAOIs, nonselective beta-blockers, alcohol, NSAIDs. Decreased levels/effects with enzyme inducers (e.g. rifampicin). Decreased hypoglycaemic effects with thiazide diuretics, corticosteroids, thyroid products and sympathomimetic agents.
Adverse Effects
1-10%
Increased uric acid (10%),Dizziness (4%),Arthropathy (3%),Flu-like syndrome,Weight gain,Hypoglycemia (2%)
Frequency Not Defined
Diarrhea,Nausea
Mechanism of Action
Nateglinide, a nonsulfonylurea hypoglycaemic agent, acts by stimulating insulin release from pancreatic ?-cells to reduce postprandial hyperglycaemia. This action depends on the amount of existing glucose levels.
Note
Nopik 120 120mg Tablet manufactured by Square Pharmaceuticals PLC.. Its generic name is Nateglinide.