Ceftor Tablet

Pharyngitis, Community-acquired pneumonia, Susceptible infections, Tonsillitis, Soft tissue infections, Respiratory tract infections, Acute Exacerbations of Chronic bronchitis

Oral Community-acquired pneumonia Adult: 400 mg bid for 14 days. Acute bacterial exacerbation of chronic bronchitis Adult: 400 mg bid for 10 days. Pharyngitis ; Tonsillitis; Uncomplicated skin and skin structure infections Adult: 200 mg bid for 10 days.

<12 years old: Safety & efficacy not established >12 years old: As in adults

Renal Impairment CrCl 30-49 mL/minute/1.73 sq. meter: No more than 200 mg PO q12hr CrCl <30 mL/minute/1.73/sq.meter: 200 mg PO qDay End-stage: Dosing not established

Should be taken with food.

Hypersensitivity to Cefditoren, other cephalosporins; or milk proteins. Carnitine deficiency.

May cause diarrhea, nausea, and vaginal moniliasis (yeast infection); pseudomembranous colitis may occur; clinical manifestations of carnitine deficiency may occur with prolonged use; prolonged use may result in emergence and overgrowth of resistant organisms; caution in breastfeeding

B Pregnancy Category: B Lactation: excretion in milk unknown; use with caution

Reduced oral bioavailability when coadministered with antacids or H2-receptor antagonists. Probenecid may increase plasma concentration and prolong the half-life of Cefditoren. May enhance the anticoagulant effect of vitamin K antagonists (e.g. warfarin). Contraindicated (0) Serious (3) BCG vaccine live cholera vaccine microbiota oral

>10% Diarrhea (11-15%) 1-10% Nausea (4-6%),Headache (2-3%),Abdominal pain (2%),Dyspepsia (1-2%),Vomiting (1%) <1% Bacterial/fungal superinfection,C. difficile colitis,Hypersensitivity,Increased bleeding time,Stevens-Johnson syndrome,Vaginal moniliasis Potentially Fatal: Hypersensitivity, anaphylaxis, Stevens-Johnson syndrome, toxic epidermal necrolysis.

Cefditoren is a third generation cephalosporin used for treatment of susceptible infections caused by gram-positive and gram-negative bacteria. It inhibits bacterial cell wall synthesis by binding to one or more of the penicillin-binding proteins (PBPs).

Ceftor 200mg Tablet manufactured by Synovia Pharma PLC. Its generic name is Cefditoren.