Erian Ointment

Internal and external haemorrhoids, Haemorrhoids post-partum, Anal pruritus, peri-anal eczema, anal fissures, proctitis, Post-haemorrhoidectomy application to relieve pain and discomfort.

Adult: Ointment Apply onto the affected area in the morning and evening and after each stool. Suppository Insert 1 suppository in the morning and evening and after each stool.

Apply the ointment in small quantity with the finger, on the painful or pruritic area, morning and evening and after each stool. For deep application attach applicator/cannula (supplied) to tube, insert to full extent and squeeze tube gently from lower end whilst withdrawing.

Known hypersensitivity to any of the four ingredients. Application to inflamed or infected tissues or to damaged skin mucosa; instillation into the middle ear. Corticosteroids have been shown to be teratogenic in animals following dermal application. As these agents are absorbed percutaneously, teratogenicity following topical application cannot be excluded. Therefore this product should not be used during pregnancy. Topical corticosteroid preparations are contraindicated in the treatment of herpes simplex, vaccinia or varicella, or tuberculous infection of the anal region.

Avoid application for prolonged periods and to extensive areas. Pregnancy, lactation.

Not Classi The safe use of topical corticosteroids during pregnancy has not been fully established. Therefore, during pregnancy, they should not be used unnecessarily on extended areas, in large amounts or for prolonged periods of time.

Restlessness; excitement; nervousness; paraesthesias; dizziness; tinnitus; blurred vision; nausea; vomiting; muscle twitching; tremors; convulsions; hypotension; bradycardia; arrhythmias; cardiac arrest. Long-term continuous treatment with topical corticosteroids should be avoided as far as possible as this may cause atrophic changes in the skin leading to thinning, loss of elasticity, dilatation of superficial blood vessels, telangiectasia and ecchymoses. These changes are particularly likely to occur when occlusive dressings are used. Systemic absorption of topically applied corticosteroids may occur, particularly under the following conditions: when large quantities are used or when application is made to wide areas of the body, or to damaged skin; when potent topical corticosteroids are used, and when the occlusive dressing technique is applied. Depression of the hypothalamic-pituitary-adrenal axis with consequent suppression of the adrenal gland may occur. These effects are most likely to be severe in children. Growth may be retarded and a Cushingoid state may be produced. Benign intracranial hypertension has been rarely reported.

Cinchocaine prevents or diminishes nerve impulse conduction near to the site of admin. It also has membrane-stabilising effect owing to decrease of permeability of the nerve cell to sodium ions. Hydrocortisone is a corticosteroid used for its anti-inflammatory and immunosuppressive effects. Its anti-inflammatory action is due to the suppression of migration of polymorphonuclear leukocytes and reversal of increased capillary permeability. It may also be used as replacement therapy in adrenocortical insufficiency. Framycetin Sulphatethe broad spectrum antibiotic,Framycetin Sulphate,eradicates most infections which may already be present or arise in lesions of the anorectal area. Esculin improves skin vasculature and is effective in the management of cellulitis.

Erian (5 mg + 5 mg + 10 mg + 10 Ointment manufactured by Square Pharmaceuticals PLC.. Its generic name is Cinchocaine HCI + Hydrocortisone + Framycetin Sulphate + Esculin (Rectal prep).